Acute Lunar Immune Dysregulation Syndrome
Earth designation: Acute Immunosuppression
Acute presentation of Immunosuppression in lunar residents. Impaired immune function from radiation exposure, chronic stress, sleep disruption, and microbial environment changes in lunar habitats. Radiation suppresses bone marrow stem cells. Chronic stress elevates cortisol, which is immunosuppressive. The highly controlled habitat microbial environment may...
Lunar Risk Factors
Cumulative radiation exposure. Chronic psychosocial stress. Sleep disruption. Microbiome changes from confined habitat. Nutritional deficiencies (vitamin D, zinc, etc.).
Symptoms
Frequent infections, prolonged illness, reactivation of latent viruses (EBV, VZV, CMV), slow wound healing.
Diagnosis
Lymphocyte count and subsets, immunoglobulin levels, NK cell function, CBC with differential.
Treatment
Address underlying causes, prophylactic antibiotics for severe cases, immunoglobulin if deficient.
Lunar Medical Bay Protocol
Optimize nutrition (zinc, vitamin D, vitamin C). Sleep protocol enforcement. Stress management. Vaccination boosters (annual influenza, VZV booster). Monitor for viral reactivation. Prophylactic acyclovir for VZV reactivation risk. Earth immunology telemedicine for significant immunodeficiency. No immunosuppressive medications unless absolutely necessary.
Evacuation Criteria
Severe combined immunodeficiency manifestation. Overwhelming infection in immunocompromised host. Bone marrow failure.
Prevention
Radiation dose monitoring and limits. Nutrition protocol. Sleep protection. Psychological support. Pre-mission vaccination completion.