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Predictive Epidemiology in Closed Habitats: Mathematical Modeling of Respiratory Outbreak Propagation: A Multicenter Analysis

Dr. L. Martinez · Lunar Medical Research Cooperative
Lunar Public Health Journal · Vol. 3, No. 2 · March 29, 2024

Abstract

Follow-up investigation building on prior work. We present mathematical models for respiratory pathogen spread in closed lunar habitats, demonstrating that standard R0 values dramatically underestimate transmission in recirculated air environments. Our models show that a single infectious arrival in a 50-person habitat can infect the majority of...

Extended analysis and updated findings. The concept of predictive epidemiology — using mathematical models to forecast outbreak patterns before they occur — has been theorized since the early 21st century. In the context of lunar habitats, it is not merely academically interesting but operationally essential: a respiratory outbreak in a 50-person habitat with a 2-week Earth resupply window is a genuine mission-threatening event.

Our compartmental models (SEIR framework modified for closed air circulation) show that standard calculation of R0 from community transmission data dramatically underestimates propagation in shared air-circulation habitats. The effective R0 for influenza in a closed lunar habitat with standard HVAC (without HEPA filtration) is approximately 8-12, compared to 1.2-3 in community settings.

The implication...

Keywords

epidemiology, outbreak, mathematical model, respiratory, quarantine, closed habitat