editorial
Vision Changes in Lunar Residents: A Prospective Registry of 214 Cases: A Case Series
Dr. T. Nguyen
· Lunar Medical Research Cooperative
Lunar Ophthalmology Reports · Vol. 3, No. 2 · November 29, 2025
Abstract
Follow-up investigation building on prior work. Vision changes affect approximately 40% of lunar residents at 12 months, with hyperopic shift being most common. This registry documents the onset, progression, and partial reversibility of vision changes, and evaluates refractive correction strategies for the lunar environment.
Extended analysis and updated findings. Visual acuity changes are among the most commonly reported health concerns of lunar residents. Our prospective registry enrolled all residents at Tycho Base Medical Center from 2027–2030.
At 12 months, 41% of residents reported subjective vision change. Objective testing confirmed hyperopic shift >0.5 diopters in 38%. Mean hyperopic shift at 24 months was +0.8 diopters. Full reversal was observed in 60% of residents within 6 months of return to Earth.
Correction strategies evaluated: progressive lenses adjusted quarterly (most effective), over-the-counter readers (+1.0 to +2.5 D stocked in medical bays), and prophylactic acetazolamide (showed modest reduction in shift rate, not recommended as standard practice due to diuretic effects).
We recommend baseline ophthalmological assessment b...
At 12 months, 41% of residents reported subjective vision change. Objective testing confirmed hyperopic shift >0.5 diopters in 38%. Mean hyperopic shift at 24 months was +0.8 diopters. Full reversal was observed in 60% of residents within 6 months of return to Earth.
Correction strategies evaluated: progressive lenses adjusted quarterly (most effective), over-the-counter readers (+1.0 to +2.5 D stocked in medical bays), and prophylactic acetazolamide (showed modest reduction in shift rate, not recommended as standard practice due to diuretic effects).
We recommend baseline ophthalmological assessment b...
Keywords
vision, hyperopia, refractive shift, optic disc, eye health, lunar